April 16, 2009

April 16, 2009

The NIAMS Update is a monthly digest published for those interested in the latest scientific news and resources on diseases of the bones, joints, muscles, and skin. We encourage further dissemination of this resource.

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Office of Communications and Public Liaison
niamsinfo@mail.nih.gov

Janet S. Austin, Ph.D.
Director

Melanie M. Martinez, M.P.A.
Public Liaison Officer

Trish Reynolds, R.N., M.S.
Media Liaison

U.S. Department of Health & Human Services and Ad Council Launch National Lupus Awareness Campaign
Eighty percent of young women in the United States say they have little or no knowledge of lupus, according to a national online survey released by the Ad Council. In an effort to raise awareness of lupus among women who are at greatest risk for the disease, the U.S. Department of Health and Human Services’ Office on Women’s Health is joining the Ad Council to launch a national multimedia public service advertising (PSA) campaign to address the disease.

The campaign is designed to heighten awareness and create a sense of urgency about lupus. With the help of women who are actually living with lupus, the Office on Women's Health is sending a message to women who are suffering from lupus symptoms-that they can find support, hope, and-most of all-answers. They just have to start by asking the right question: "Could I have lupus?" Learn more about the National Lupus Awareness Campaign.


Students and Science Educators To Get Boost from NIH ARRA Initiative
The National Institutes of Health (NIH) recently announced American Recovery and Reinvestment Act (ARRA) funding for administrative supplements to existing NIH grants and $21 million over 2 years has been allocated for educational opportunities in NIH-funded laboratories for students and science educators.

NIH Announces ARRA Funding Opportunities: $1 Billion Available for Extramural Core Facilities and Other Construction, Renovation, or Repair Awards
NIH announced some of the new funding opportunities made possible through ARRA. One billion dollars of the $10.4 billion provided to NIH under ARRA has been allocated for Federal awards to institutions seeking to construct, renovate, or repair biomedical or behavioral research facilities. The National Center for Research Resources (NCRR), a part of NIH, will administer these categories of grants.

Biomedical Researchers Invited to Design Experiments for the International Space Station
NIH and the National Air and Space Administration (NASA) are partnering to conduct biomedical experiments that astronauts could perform on the International Space Station. In a notice to scientists at universities, medical centers, and companies across the United States, NIH announced its willingness to fund highly meritorious biomedical experiments that could utilize the unique environment in space and produce breakthroughs to improve human health on Earth.

NIAMS Scientists Discover a New Source of Progenitor Cells in Traumatized Tissue
NIAMS scientists have discovered that tissue removed from traumatic wounds, traditionally considered medical waste, can be a source of progenitor cells. These cells feature many of the same properties as adult stem cells, particularly in that they have the capacity to differentiate into a specific type of cell. Researchers are currently studying ways to use progenitor cells to improve healing at the site of an injury, and traumatized tissue may provide an alternative source of cells for these therapies. The findings were recently published in two research reports in the Journal of Bone and Joint Surgery and the Journal of Tissue Engineering and Regenerative Medicine.

A Key to Understanding Lymphoma
Lymphoma is the most common blood cancer and the third most common childhood cancer in the United States. Although there are many types of lymphoma, they all originate in the white blood cells (lymphocytes) that are part of the immune system. These cells are meant to protect the body against infection, but sometimes they become diseased themselves. The exact cause of this cancer is unknown, but now researchers funded by NIAMS have made a scientific advance that could lead to new therapies.

Scientists Discover Interactions of Different Immune Cell Populations in Lupus
Research supported by NIAMS offers new insight into the cellular mechanisms of systemic lupus erythematosus (SLE), or lupus, a disabling and sometimes life-threatening disease that affects as many as 322,000 Americans, mostly women. The new finding brings scientists one step closer to understanding the cellular events that lead to lupus, a disease which has not been clearly defined. They say the results of this work will help explain why B cells are so promising and will add support to the need for further development of B-cell-focused treatments for the disease.

Researchers Develop DNA "Patch" for Canine Form of Muscular Dystrophy: Finding Lays the Foundation for Human Testing
Using a novel genetic technology that covers up genetic errors, researchers funded in part by NIH have developed a successful treatment for dogs with the canine version of Duchenne muscular dystrophy, a paralyzing, and ultimately fatal, muscle disease.

The Rocket Boys of NIH-New Children's Book Released
The NIH Center for Scientific Review (CSR) has announced a new children's book that tells the trials and triumphs of NIH's youngest researchers: The Rocket Boys of NIH: How NIH Gives Health and Hope to Kids and the World. The book is written at a reading level suitable for fourth or fifth graders and can be enjoyed by older readers.

NIH Research Matters: Vitamin C May Reduce Risk of Gout
A new study has linked higher vitamin C intake with a lower risk of gout. Vitamin C supplements, the results imply, may help to prevent gout.

NIH Research Matters: Thwarting Fungal Defenses
Researchers have devised a way to stymie fungi's ability to become resistant to antifungal drugs. The advance paves the way for future therapies to treat fungal infections, a leading cause of death for people with weakened immune systems.

NIH Public Bulletin 
Read about the latest public events, activities, and health information resources from NIH in the latest issue of the NIH Public Bulletin.

NIH News in Health 
Read practical health information in NIH News in Health, which is reviewed by NIH’s medical experts and is based on research conducted either by NIH's own scientists or by our grantees at universities and medical schools around the country.

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Lower Socioeconomic Status Results in Poor Physical and Mental Health Outcomes for Patients with Lupus
Systemic lupus erythematosus (SLE) is an autoimmune disease that predominantly affects women. Patients with SLE have twice the risk of dying compared to the general population. Socioeconomic status (SES) of patients-as well as their neighborhoods-can impact SLE outcomes. Researchers from the University of California, San Francisco found that patients with SLE who also are in low SES have worse physical functioning and more depressive symptoms. The study was supported in part by AHRQ.

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Moving Into the Future: New Dimensions and Strategies for Women's Health Research for the National Institutes of Health

NIH’s Office of Research on Women's Health and the Department of Obstetrics, Gynecology, and Reproductive Sciences at the University of California, San Francisco (UCSF) are convening the second in a series of public hearings and scientific workshops to update the Women's Health Research Agenda at NIH for the coming decade.

May 27 to 29, 2009
Mission Bay Conference Center at UCSF
1675 Owens Street
San Francisco, CA 94158

Save the Date: NIAMS Advisory Council Meeting
The next NIAMS Advisory Council Meeting will be held June 2, 2009, in Building 31, 6th floor, C Wing, Conference Room 6, NIH Campus.

AAOS/ORS 2008 Research Symposium Proceedings Published
The proceedings of the American Academy of Orthopaedic Surgeons (AAOS)/Orthopaedic Research Society (ORS) 2008 Research Symposium, "Advanced Imaging and Computer-Assisted Surgery of the Knee and Hip," were published in February 2009 as a supplement to the Journal of Bone and Joint Surgery (JBJS). The symposium was partly funded by NIAMS.

NIAMS Advisory Council September 2008 Meeting Minutes Are Available
The 66th meeting of the NIAMS Advisory Council was held on September 23, 2008, at the NIH Campus. The meeting was chaired by Dr. Stephen I. Katz, NIAMS Director.

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The following new fact sheets are now available on the NIAMS Web site. They are part of our easy-to-read “Fast Facts” series of publications for the public.
 

Fast Facts about Juvenile Arthritis
Fast Facts about Bursitis and Tendinitis

Revised Publication:
 

The Many Shades of Lupus
Lupus has many shades. It can affect people of different races, ethnicities, and ages, both men and women. It can look like different diseases. It's different for every person who has it. The people you live with and work with may have trouble understanding that you're sick. Lupus doesn't have a clear set of signs that people can see. You may know that something's wrong, even though it may take a while to be diagnosed. The good news is that you can get help and fight lupus. Learning about it is the first step. Ask questions. Talk to your doctor, family, and friends. People who look for answers are more likely to find them. This booklet can help you get started.


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American Recovery and Reinvestment Act of 2009

Recovery Act Limited Competition for NIH Grants: Research and Research Infrastructure Grand Opportunities (RC2)
(RFA-OD-09-004)
Letters of Intent Receipt Date: April 27, 2009
Application Receipt Date: May 27, 2009


Recovery Act Limited Competition: Supporting New Faculty Recruitment to Enhance Research Resources through Biomedical Research Core Centers (P30)
(RFA-OD-09-005)
Letters of Intent Receipt Date: April 29, 2009
Application Receipt Date: May 29, 2009


Recovery Act Notice: NIH ARRA Funding Considerations for Applications with Meritorious Scores that Fall Beyond the Pay-line
(NOT-OD-09-078)


ARRA Administrative Supplements and Competitive Revisions: Clarifications on Programmatic Limitations and Use of Modular Budgets
(NOT-OD-09-079)


Recovery Act of 2009: NIH Award Terms and Additional Information for Recipients Receiving Recovery Act Grant Funding
(NOT-OD-09-080)


Recovery Act of 2009: NIH Review Criteria, Scoring System, and Suspension of Appeals Process
(NOT-OD-09-054)


NIH Announces the Availability of Recovery Act Funds for Administrative Supplements
(NOT-OD-09-056)


NIH Announces the Availability of Recovery Act Funds for Competitive Revision Applications
(NOT-OD-09-058)


NIH Announces the Availability of Recovery Act Funds for Administrative Supplements Providing Summer Research Experiences for Students and Science Educators
(NOT-OD-09-060)


Clarification to RFA-OD-09-003-Recovery Act Limited Competition: NIH Challenge Grants in Health and Science Research (RC1)
(NOT-OD-09-061)


Addition of Recovery Funds to the Shared Instrumentation Grant Program
(NOT-RR-09-008)


Web Seminar Regarding Application Process for RFA-RR-09-007 (Core Facilities Improvement Projects) and RFA-RR-09-008 (Construction, Renovation, and Repair Improvement Projects)
(NOT-RR-09-009)


Videocast Regarding Application Process for RFA-RR-09-007 (Core Facilities Improvement Projects) and RFA-RR-09-008 (Construction, Renovation, and Repair Improvement Projects)
(NOT-RR-09-010)


Notice Regarding RFA-OD-09-005, "Recovery Act Limited Competition: Biomedical Research Core Centers to Enhance Research Resources (P30)"
(NOT-OD-09-076)


NIH Roadmap Initiative Announcements

Novel Statistical Methods for Human Gene Expression Quantitative Trait Loci (eQTL) Analysis (R01) 
(RFA-RM-09-006)
Letters of Intent Receipt Date: August 16, 2009
Application Receipt Date: September 16, 2009


NIH-RAID Administrative Supplements for Preclinical Efficacy Testing of Candidate Therapeutics
(NOT-RM-09-010)


Other Research Announcements

Replication, Fine-Mapping, and Sequencing: Follow-Up on Genome-Wide Association Studies for Arthritis and Musculoskeletal and Skin Diseases (R01)
(PAR-09-135)
Letters of Intent Receipt Dates: August 31, 2009; June 1, 2010; June 1, 2011
Application Receipt Dates: September 29, 2009; June 29, 2010; June 29, 2011


Clarification on the Council Review Date for the NIAMS Building Interdisciplinary Research Team (BIRT) Revision Awards (RFA-AR-09-002)
(NOT-AR-10-013)


Biobehavioral Methods To Improve Outcomes Research (R01) 
(PA-09-125)
Letters of Intent Receipt Date: Not Applicable
Application Receipt Dates: Multiple dates, see announcement


Biobehavioral Methods To Improve Outcomes Research (R21)
(PA-09-126)
Letters of Intent Receipt Date: Not Applicable
Application Receipt Dates: Multiple dates, see announcement


Biomedical Research on the International Space Station (BioMed-ISS) (UH2/UH3)
(PAR-09-120)
Letters of Intent Receipt Dates: August 31, 2009, 2010, 2011
Application Receipt Dates: September 30, 2009, 2010, 2011


Clarification on Required Budget Forms for Grant Applicants Submitting in Response to PA-07-318
(NOT-OD-09-059)


Extension of Expiration Date for PA-07-277, PA-06-367, and PA-06-368 Research on Ethical Issues in Human Subjects Research 
(NOT-OD-09-062)


NIH Announces its 2009 SBIR/STTR Conference (June 30 to July 1, 2009) 
(NOT-OD-09-063)


IACUC 101 and 201 PLUS Workshops: April 22 to 23, 2009, in Washington, DC 
(NOT-OD-09-065)


NIH Fiscal Policy for Grant Awards-FY 2009 
(NOT-OD-09-066)


Announcing the FY 2009 NIH Directors Bridge Awards
(NOT-OD-09-068)


Salary Limitation on Grants, Cooperative Agreements, and Contracts 
(NOT-OD-09-069)


Notice of Legislative Mandates in Effect for FY 2009 
(NOT-OD-09-070)


The Omnibus Appropriations Act of 2009 Makes the NIH Public Access Policy Permanent
(NOT-OD-09-071)


NIH Requires Mandatory Use of the eRA Commons Financial Conflict of Interest (FCOI) Module beginning July 1, 2009, for NIH-funded Grants and/or Cooperative Agreements
(NOT-OD-09-072)


Enhancing Peer Review: NIH Announces Consolidation of Review Criteria for Institutional Research Training Grant Applications (T32) Submitted for FY 2010 Funding
(NOT-OD-09-074)


Ruth L. Kirschstein National Research Service Award (NRSA) Stipend and Other Budgetary Levels Effective for Fiscal Year 2009
(NOT-OD-09-075)


Notice of Public Meeting: Expansion of the Clinical Trials Registry and Results Data Bank 
(NOT-OD-09-077)

If you would like to review information about funding opportunities more frequently than our monthly updates allow, see the NIH Guide to Grants and Contracts, the primary source for information about NIH funding opportunities. You can also request a weekly Table of Contents from the NIH Guide.


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